![]() Further studies are needed to confirm this finding using larger number of samples and involving various age group. However Bifidobacterium, Lactobacillus and Clostridium difficile could be found. These data indicated that aerob and facultative anaerob bacteria were predominant in neonates. Enterobacteriaceae were found to be dominant isolates (25% - 75%) followed by Streptococcus anhaemolyticus (60%), Staphylococcus epidermidis (40%), Staphylococcus aureus (5%),Clostridium difficile (5%), Bacteroides fragilis (5%), Bifidobacterium sp. Aerob and anaerob bacterial species were isolated from all samples, ranged 2 ? 5 species per sample. Bacteriological cultures for aerob and anaerob bacteria were performed according to the standard methods. All samples were sent to microbiology laboratory without transport media and processed immediately. This study included samples taken from 20 neonates, age 1 ? 7 days, from a private hospital in Jakarta. This preliminary study is to establish local reference of microbial flora in neonates. Ada beberapa hipotesis mengenai anaerob obligat yang sensitif terhadap oksigen. Factors influencing intestinal microflora are environment, genetic predisposition, diet, age, diseases, drugs, stressor. Mikroba anaerob obligat yang sensitif terhadap oksigen memperoleh energi dan melakukan metabolisme dengan menggunakan beberapa alternatif akseptor elektron untuk respirasi seluler seperti sulfat, nitrat, besi, mangan, merkuri, dan karbon monoksida. Recent published data have outlined a relationship between the composition of the intestinal microflora and allergic inflammation, autoimmunity, chronic bowel inflammation, psychiatric, cognitive and behavioral disturbances.
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